The Cowboys, who have lost three straight and are playing with only four healthy offensive linemen, are just 1-5 in their last nine games and are 0-5 overall.
The Panthers, meanwhile, are 6-2 in their past seven games, including a 24-17 win over the Cardinals on Monday night.
The NFC South is currently the NFC’s fourth-best division and the Panthers are a two-point favorite over Dallas.
Carolina has won five straight against Dallas, and the Cowboys are 7-1 in those games.
Carolina’s only losses have come to Dallas and New Orleans, and it has won seven straight against the Saints.